Which setting should you use to define the extent when users click New Map from your organization's ArcGIS Online site?

The setting to define the extent when users click New Map from your organization's ArcGIS Online site is found in the Map and Scene Defaults. This feature allows you to specify initial settings for new maps, including the geographic extent, basemaps, and whether to show a specific layer. By configuring these defaults, administrators can ensure that all new maps created within their organization start with the same spatial reference and extent, which is especially helpful for maintaining consistency in mapping projects.

Choosing the right default extent can enhance user experience by guiding them to relevant geographical areas or data of interest right from the start. This is crucial for organizations that require a standardized approach to mapping and want to promote efficiency among users who may have varying levels of experience with the mapping tools in ArcGIS Online.

The other options, while relevant to different aspects of ArcGIS Online, do not pertain to defining the initial extent of a new map. Analysis Layers are used for performing geographic analysis, Web Styles focus on defining the aesthetic elements of maps, and the Primary Map Viewer relates to the user interface experience but does not set initial map extents. Thus, the option related to Map and Scene Defaults is the most appropriate choice for establishing map extent settings.